Publications
Prof. Dr. Schambony
2024
Noncanonical WNT5A controls the activation of latent TGF-β to drive fibroblast activation and tissue fibrosis
In: Journal of Clinical Investigation 134 (2024)
ISSN: 0021-9738
DOI: 10.1172/JCI159884 , , , , , , , , , , , , , , , , , , , , , , , :
2020
Molecular cross-talk between Y5-receptor and neuropeptide Y drives liver cancer
In: Journal of Clinical Investigation 130 (2020), p. 2509-2526
ISSN: 0021-9738
DOI: 10.1172/JCI131919 , , , , , , , , , , , , , , , , :
Lipid Dynamics in Membranes Slowed Down by Transmembrane Proteins
In: Frontiers in Cell and Developmental Biology 8 (2020)
ISSN: 2296-634X
DOI: 10.3389/fcell.2020.579388 , , , , , , , :
Label-free live-cell imaging with interferometric scattering microscopy: Confocal imaging and high-speed 3D single particle tracking
Microscopy Histopathology and Analytics, Microscopy 2020 (Washington, DC, April 20, 2020 - April 23, 2020)
In: Optics InfoBase Conference Papers 2020
DOI: 10.1364/MICROSCOPY.2020.MW1A.4 , , , , , :
High-Precision Protein-Tracking With Interferometric Scattering Microscopy
In: Frontiers in Cell and Developmental Biology 8 (2020), Article No.: 590158
ISSN: 2296-634X
DOI: 10.3389/fcell.2020.590158 , , , , , , , :
2019
Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1
In: Nature Communications 10 (2019), Article No.: 1804
ISSN: 2041-1723
DOI: 10.1038/s41467-019-09651-7 , , , , , , , , , , , , , , , , , , , , :
High-resolution, three-dimensional investigation of protein diffusion and trafficking in the live HeLa cell via interferometrie scattering microscopy (iSCAT)
2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019 (Munich, June 23, 2019 - June 27, 2019)
In: 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019 2019
DOI: 10.1109/CLEOE-EQEC.2019.8872206 , , , :
Interferometric scattering microscopy reveals microsecond nanoscopic protein motion on a live cell membrane
In: Nature Photonics (2019)
ISSN: 1749-4885
DOI: 10.1038/s41566-019-0414-6 , , , , , :
2018
Pgam5 released from damaged mitochondria induces mitochondrial biogenesis via Wnt signaling
In: The Journal of Cell Biology 217 (2018), p. 1383-1394
ISSN: 0021-9525
DOI: 10.1083/jcb.201708191 , , , , , , :
Erratum to: Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo (Nature Communications, (2018), 9, 1, (3846), 10.1038/s41467-018-06368-x)
In: Nature Communications 9 (2018), Article No.: 4633
ISSN: 2041-1723
DOI: 10.1038/s41467-018-07167-0 , , , , , , :
EFHD2/SWIPROSIN-1 IS A CONSERVED RESILIENCE FACTOR AGAINST ALCOHOL DRINKING ESCALATION , , , , , , , , , :
2017
Dishevelled Paralogs in Vertebrate Development: Redundant or Distinct?
In: Frontiers in Cell and Developmental Biology 5 (2017), p. 59
ISSN: 2296-634X
DOI: 10.3389/fcell.2017.00059 , :
EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction
In: Molecular Psychiatry 23 (2017), p. 1303-1319
ISSN: 1476-5578
DOI: 10.1038/mp.2017.63 , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , :
hmmr mediates anterior neural tube closure and morphogenesis in the frog Xenopus
In: Developmental Biology 430 (2017), p. 188-201
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2017.07.020 , , , , :
The phosphatase Pgam5 antagonizes Wnt/β-catenin signaling in embryonic anterior-posterior axis patterning
In: Development 144 (2017), p. 2234-2247
ISSN: 1477-9129
DOI: 10.1242/dev.144477 , , , , , , , :
Signaling pathways and tissue interactions in neural plate border formation
In: Neurogenesis 4 (2017), p. e1292783
ISSN: 2326-2133
DOI: 10.1080/23262133.2017.1292783
URL: https://www.tandfonline.com/doi/full/10.1080/23262133.2017.1292783 , :
ROR-Family Receptor Tyrosine Kinases.
In: Current Topics in Developmental Biology 123 (2017), p. 105-142
ISSN: 0070-2153
DOI: 10.1016/bs.ctdb.2016.09.003
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28236965&retmode=ref&cmd=prlinks , , :
2016
β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases.
In: Clinical & Experimental Metastasis 33 (2016), p. 309-323
ISSN: 0262-0898
DOI: 10.1007/s10585-016-9780-3
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26862065&retmode=ref&cmd=prlinks , , , , , , , , , , , , , , :
WNT5A PROMOTES FIBROBLAST ACTIVATION AND TISSUE FIBROSIS BY ROR2/RYK DEPENDENT ACTIVATION OF PCP-SIGNALING , , , , , , , , :
The function of the two-pore channel TPC1 depends on dimerization of its carboxy-terminal helix.
In: Cellular and Molecular Life Sciences 73 (2016), p. 2565-81
ISSN: 1420-682X
DOI: 10.1007/s00018-016-2131-3 , , , , , :
Ror2 signaling is required for local upregulation of GFD6 and activation of BMP signaling at the neural plate border
In: Development 143 (2016), p. 3182-3194
ISSN: 1477-9129
DOI: 10.1242/dev.135426 , , , :
Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development.
In: Bmc Developmental Biology 16 (2016), p. 1
ISSN: 1471-213X
DOI: 10.1186/s12861-016-0101-5
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26780949&retmode=ref&cmd=prlinks , , :
2015
Distinct functionality of dishevelled isoforms on Ca2+/calmodulin-dependent protein kinase 2 (CamKII) in Xenopus gastrulation.
In: Molecular Biology of the Cell 26 (2015), p. 966-977
ISSN: 1059-1524
DOI: 10.1091/mbc.E14-06-1089
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25568338&retmode=ref&cmd=prlinks , , , :
2014
Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5.
In: Journal of Biological Chemistry 289 (2014), p. 23520-23533
ISSN: 0021-9258
DOI: 10.1074/jbc.M114.590638
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24993822&retmode=ref&cmd=prlinks , , , , , , , , :
Molecular Mechanisms of Wnt Pathway Specificity
In: Hoppler SP, Moon RT (ed.): Wnt Signaling in Development and Disease, John Wiley & Sons, 2014, p. 101-112
ISBN: 1118444094
DOI: 10.1002/9781118444122.ch7 , , :
β-Arrestin interacts with the beta/gamma subunits of trimeric G-proteins and dishevelled in the Wnt/Ca(2+) pathway in xenopus gastrulation.
In: PLoS ONE 9 (2014), Article No.: e87132
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0087132
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24489854&retmode=ref&cmd=prlinks , , , , , :
2013
HOX genes regulate Rac1 activity in hematopoietic cells through control of Vav2 expression
In: Leukemia 27 (2013), p. 236-238
ISSN: 0887-6924
DOI: 10.1038/leu.2012.166 , , , , , , :
2012
Amer2 protein interacts with EB1 protein and adenomatous polyposis coli (APC) and controls microtubule stability and cell migration.
In: Journal of Biological Chemistry 287 (2012), p. 35333-35340
ISSN: 0021-9258
DOI: 10.1074/jbc.M112.385393
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=22898821&retmode=ref&cmd=prlinks , , , , :
Amer2 protein is a novel negative regulator of Wnt/β-catenin signaling involved in neuroectodermal patterning.
In: Journal of Biological Chemistry 287 (2012), p. 1734-1741
ISSN: 0021-9258
DOI: 10.1074/jbc.M111.308650
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=22128170&retmode=ref&cmd=prlinks , , , :
19th Acta Physiologica international symposium ‘WNT Signaling in Physiology and Disease’– a long way from developmental biology to physiology
In: Acta Physiologica 204 (2012), p. 6-7
ISSN: 1748-1708
DOI: 10.1111/j.1748-1716.2011.02326.x
URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1748-1716.2011.02326.x/full , , :
Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled.
In: Proceedings of the National Academy of Sciences of the United States of America 109 (2012), p. E812-20
ISSN: 0027-8424
DOI: 10.1073/pnas.1114802109
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=22411803&retmode=ref&cmd=prlinks , , , , , , , , , , :
2011
PAPC and the Wnt5a/Ror2 pathway control the invagination of the otic placode in Xenopus.
In: Bmc Developmental Biology 11 (2011), p. 36
ISSN: 1471-213X
DOI: 10.1186/1471-213X-11-36
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21663658&retmode=ref&cmd=prlinks , , , :
Waif1/5T4 inhibits Wnt/β-catenin signaling and activates noncanonical Wnt pathways by modifying LRP6 subcellular localization.
In: Developmental Cell 21 (2011), p. 1129-1143
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2011.10.015
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=22100263&retmode=ref&cmd=prlinks , , , , , , , , , , :
Structural and functional characterization of the Wnt inhibitor APC membrane recruitment 1 (Amer1).
In: Journal of Biological Chemistry 286 (2011), p. 19204-19214
ISSN: 0021-9258
DOI: 10.1074/jbc.M111.224881
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21498506&retmode=ref&cmd=prlinks , , , , , :
2010
Wnt5a/Ror2-induced upregulation of xPAPC requires xShcA.
In: Biochemical and Biophysical Research Communications 400 (2010), p. 500-506
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2010.08.074
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20732301&retmode=ref&cmd=prlinks , , , :
Prohibitin1 acts as a neural crest specifier in Xenopus development by repressing the transcription factor E2F1
In: Development 137 (2010), p. 4073-4081
ISSN: 1477-9129
DOI: 10.1242/dev.053405 , , :
β-arrestins - Scaffolds and signalling elements essential for WNT/Frizzled signalling pathways?
In: British Journal of Pharmacology 159 (2010), p. 1051-1058
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.2009.00466.x , , :
Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2.
In: The FASEB Journal 24 (2010), p. 2417-2426
ISSN: 0892-6638
DOI: 10.1096/fj.09-150615
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20215527&retmode=ref&cmd=prlinks , , , , , , , , , :
2009
The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo.
In: Molecular Biology of the Cell 20 (2009), p. 924-936
ISSN: 1059-1524
DOI: 10.1091/mbc.E08-07-0711
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=19056682&retmode=ref&cmd=prlinks , , , , , , , , , , , :
The LIM domain protein Wtip interacts with the receptor tyrosine kinase Ror2 and inhibits canonical Wnt signalling.
In: Biochemical and Biophysical Research Communications 390 (2009), p. 211-216
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2009.09.086
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=19785987&retmode=ref&cmd=prlinks , , , , , , :
2008
Isothiocyanate-functionalized RGD peptides for tailoring cell-adhesive surface patterns.
In: Biomaterials 29 (2008), p. 3004-3013
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2008.04.003
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=18433862&retmode=ref&cmd=prlinks , , , , , , , , , :
2007
Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo.
In: Proceedings of the National Academy of Sciences of the United States of America 104 (2007), p. 6690-6695
ISSN: 0027-8424
DOI: 10.1073/pnas.0611356104
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=17426148&retmode=ref&cmd=prlinks , , , , :- Köhler A, Schambony A, Wedlich D:
Cell migration under control of Wnt‐signaling in the vertebrate embryo
In: Advances in Developmental Biology (2007)
ISSN: 1574-3349
DOI: 10.1016/S1574-3349(06)17005-2
URL: http://www.sciencedirect.com/science/article/pii/S1574334906170052
Wnt-5A/Ror2 regulate expression of XPAPC through an alternative noncanonical signaling pathway.
In: Developmental Cell 12 (2007), p. 779-792
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2007.02.016
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=17488628&retmode=ref&cmd=prlinks , :
2004
Cross-regulation of Wnt signaling and cell adhesion.
In: Differentiation 72 (2004), p. 307-318
ISSN: 0301-4681
DOI: 10.1111/j.1432-0436.2004.07207002.x
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=15554942&retmode=ref&cmd=prlinks , , :
Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK.
In: EMBO Journal 23 (2004), p. 3259-3269
ISSN: 0261-4189
DOI: 10.1038/sj.emboj.7600332
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=15297873&retmode=ref&cmd=prlinks , , , , , :
2003
- Liao Q, Kleeff J, Xiao Y, Guweidhi A, Schambony A, Töpfer-Petersen E, Zimmermann A, Büchler MW, Friess H:
Preferential expression of cystein-rich secretory protein-3 (CRISP-3) in chronic pancreatitis.
In: Histology and Histopathology 18 (2003), p. 425-433
ISSN: 0213-3911
DOI: 10.14670/HH-18.425
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=12647793&retmode=ref&cmd=prlinks
A homologue of cysteine-rich secretory proteins induces premature degradation of vitelline envelopes and hatching of Xenopus laevis embryos.
In: Mechanisms of Development 120 (2003), p. 937-948
ISSN: 0925-4773
DOI: 10.1016/S0925-4773(03)00162-X
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=12963113&retmode=ref&cmd=prlinks , , , , :
Wnt Signaling and Cell Migration
In: Michael Kühl (ed.): Wnt Signaling in Development, Springer Science & Business Media, 2003, p. 240-250
ISBN: 0306478382, 9780306478383 , :
2002
- Giese A, Jude R, Kuiper H, Piumi F, Schambony A, Guérin G, Distl O, Töpfer-Petersen E, Leeb T:
Molecular characterization of the equine AEG1 locus.
In: Gene 292 (2002), p. 65-72
ISSN: 0378-1119
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=12119100&retmode=ref&cmd=prlinks
1998
- Schambony A, Gentzel M, Wolfes H, Raida M, Neumann U, Töpfer-Petersen E:
Equine CRISP-3: primary structure and expression in the male genital tract.
In: Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 1387 (1998), p. 206-216
ISSN: 0167-4838
DOI: 10.1016/S0167-4838(98)00122-8
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=9748582&retmode=ref&cmd=prlinks - Schambony A, Hess O, Gentzel M, Töpfer-Petersen E:
Expression of CRISP proteins in the male equine genital tract.
In: Journal of reproduction and fertility. Supplement 53 (1998), p. 67-72
ISSN: 0449-3087
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=10645267&retmode=ref&cmd=prlinks - Töpfer-Petersen E, Waberski D, Hess O, Bellair S, Schambony A, EKHLASI-HUNDRIESER M, Gentzel M, REINEKE A:
The role of seminal plasma in fertilisation
In: Tieraerztliche Umschau 53 (1998), p. 447-454
ISSN: 0049-3864
URL: http://espace.library.uq.edu.au/view/UQ:280792
1997
- Magdaleno L, Gasset M, Varea J, Schambony AM, Urbanke C, Raida M, Töpfer-Petersen E, Calvete JJ:
Biochemical and conformational characterisation of HSP-3, a stallion seminal plasma protein of the cysteine-rich secretory protein (CRISP) family.
In: FEBS letters 420 (1997), p. 179-185
ISSN: 1873-3468
DOI: 10.1016/S0014-5793(97)01514-7
URL: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=9459306&retmode=ref&cmd=prlinks